Click here to read more. Previous question Next question Get more help from Chegg. Synthesizes Cholesterol And Fat - Find out how cholesterol is synthesized. But too much cholesterol can pose a problem. Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D.Cholesterol is the principal sterol synthesized by all animals. Your liver makes all the cholesterol you need. Cholesterol levels in the body originate from its biosynthesis and diet. Note that significant amounts of cholesterol only occur in meat, eggs, and milk products; plants and mushrooms contain other sterols but very little cholesterol. Cholesterol is a waxy substance. The remainder of the cholesterol in your body comes from foods from animals. The primary bile acids are synthesized in the liver from cholesterol. Where is cholesterol synthesized? The molecule. Biosynthesis of cholesterol commonly happens in the endoplasmic reticulum of hepatic cells. Cholesterol can also be obtained from food. Most of the cholesterol used by active adults is produced in the liver, which produces ~70% of daily cholesterol demand (~1 gram). The total number of stereocenters is 8. Cholesterol is a tetracyclic alcohol and a type of sterol.Added to the sterol frame with the alcohol group at position 3 are 2 methyl groups at carbon positions 10 and 13 and a 2-isooctyl group at position 17. Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. Cholesterol can both be synthesized endogenously and obtained from the diet. The other 30% originates from dietary absorption. These are cholic acid (found in the largest amount) and chenodeoxycholic acid (Figure 26–7). Cholesterol comes from two sources. In vertebrates, hepatic cells typically produce the greatest amounts. A typical North American diet contains approximately 450mg of cholesterol per day (of which 55% is absorbed), while cholesterol synthesis on such a modest cholesterol diet is 11–13mg/kg/day. It is synthesized from simpler substances within the body. Cholesterol is present in tissues and in plasma either as free cholesterol or combined with a long-chain fatty acid as cholesteryl ester, the storage form. Cholesterol is synthesized by virtually all tissues in human, although liver, intestine, adrenal cortex, reproductive organs (testis and ovaries) and placenta make largest contributions to the body’s cholesterol pool. The molecule is unsaturated at position 5,6 with an alkene group. Acetyl-CoA is produced from glucose by the same sequence of reactions used to produce cytosolic acetyl-CoA for fatty acid biosynthesis. Expert Answer . It’s not inherently “bad.” Your body needs it to build cells and make vitamins and other hormones. 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